Explains human aging from genes to clinical disease. With over 4,000 references, this book explores both the fundamental processes of aging and the resultant tissue-by-tissue clinical pathology, detailing both research and state-of-the art clinical interventions in aging and age-related disease. ...this book is an imporatant contribution on aging - especially cell senescene - and it, hopefully, stimulates researchers to have a closer more open-minded look at this vital biological process.